![]() We report a case of a COVID-19 patient’s presentation with Acute Hypoxemic respiratory failure and refractive hypoxemia argyria. The bluish coloration in combination with the deposits of silver in the tissues can affect oxygen transport and cause severe hypoxemia and low saturations. When these patients present with COVID-19 and have profound hypoxemia due to reduced oxygen transport. Other conditions that can cause pseudocyanosis include methemoglobinemia, medication induced such as Amiodarone, Minocycline and antimalarial medications, hemosiderosis, Wilson disease, heavy metal ingestion of mercury and gold. The cases keep decreasing and the number of patients with this form of pseudocyanosis continues to decline worldwide. Fortunately, this condition is becoming rare as medications containing silver are not widely used and when used it is for short period of time. #Colloidal silver blue skin skin#This bluish coloration of the nail beds and skin can be the same presentation as cyanosis. Chelating agents have no role in removing the silver, although laser therapy seems to be an emerging treatment option with limited improvement. There is no definite therapy for this condition. ![]() It is believed that silver compounds form complexes with proteins in the skin which reduce to elemental silver when exposed to light, similar to the process of photo imaging. This passive photosensitivity reaction leads to silver tattooing of the light-exposed skin. The discoloration can become permanent due to the changes in melanin, the grey blue discoloration becomes permanent and predominates on sun exposed areas. This is a very rare condition as use of silver compounds and work exposure in the manufacturing process of silver has increased regulations to protect workers. Pigmentation is permanent but benign, causing only an aesthetic concern. Skin biopsy confirms the diagnosis by demonstrating tiny brownish granules in connective tissue surrounding sebaceous glands, in perineural tissue and in arteriolar walls. It is characterized by a blue – gray discoloring that can occur on the skin and mucous membranes. MeSH Keywords : Argyria, hypoxemia, endotracheal intubation, Silver, ARDS, Melanin, COVID-19, Human, dietary supplement, cyanosis, hypoxemia, Pseudocyanosis, Heavy metal poisoning, blue man.Īrgyria is rare skin disease caused by cutaneous deposition of silver granules on the skin, due to chronic consumption or contact with silver salts. Chang, M.D., M.B.A, this is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Chang, M.D., M.B.A., Clinical Assistant Professor of Medicine University of Texas Medical Branch, TexasĬopy Right: © 2021 Eduardo E. ![]() Senior Patient Liaison, Methodist Hospital, Houston TexasĬorresponding Author: Eduardo E. Physiotherapist, Cardiovascular & Respiratory Specialist, Universidad del Rosario, Colombia.ģ. Pulmonary, Sleep, Critical Care Specialist, Clinical Assistant Professor of Medicine, University of Texas Medical Branch, Texas, The Lung Institute, Houston Texas.Ģ. Chang, M.D 1, Diana Maria Salamanca 2, Esther Segura M.D. ![]() Refractory Hypoxic Respiratory Failure in a Pseudo Cyanotic COVID-19 Patient with Argyria Due to Chronic Colloidal Silver Supplement.Įduardo E. ![]()
0 Comments
Leave a Reply. |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |